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Updated: May 15, 2026

A Two-Step Protocol for Umpolung Functionalization of Ketones Via Enolonium Species
Published on: August 16, 2018
1-(2-Hy-droxy-5-meth-oxy-phen-yl)-3-methyl-but-2-en-1-one
Catherine Thomas Alexander1, David Vargas, Frank R Fronczek
1Department of Chemistry, Louisiana State University, Baton Rouge LA 70803-1804 USA.
Abstract:
The title compound, C(12)H(14)O(3), is a natural product derived from the medium-sized hawthorn Crataegus persimilis ('prunifolia'). The mean plane of the butene moiety is twisted by 13.27 (7)° with respect to the that of the dioxobenzaldehyde moiety. There is an intra-molecular hydrogen bond between the hydroxyl group and the carbonyl O atom.
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