Related Experiment Video
Updated: May 15, 2026

In Vivo Telemetry to Record Long-Term Cardiovascular Parameters, Temperature, and Activity in Spinal Cord Injury Rat Models
Published on: January 2, 2026
Loss of Consciousness in Injuries of the Extremities is an Alert to a Higher Probability of Death
José Eduardo Arantes Sanches1, José Maria Pereira de Godoy, André Luciano Baitello
1Department of Orthopedic and Traumatology in Medicine School of São Jose do Rio Preto, FAMERP, Brazil.
Background:
There are many published studies about loss of consciousness related to general trauma however works on loss of consciousness in respect to orthopedic injuries are scarce.
Aim:
The aim of this study was to investigate whether loss of consciousness worsens the prognosis of patients with orthopedic injuries.
Method:
A retrospective cohort study of orthopedic traumas was performed in the university Hospital of Base in São José do Rio Preto. All accident victims with injuries of the extremities classified as Score 3 or 4 by the Abbreviated Injury Scale (AIS) were included in this observational quantitative study. Patients with minor injuries and injuries that did not involve the extremities were not included. The association of loss of consciousness at the scene of the accident with evolution to death was investigated. The t-test, chi-squared and Fisher exact tests, and relative risk were used for statistical analysis. An alpha error of 5% (p-value ≤ 0.05) was considered statistically significant.
Results:
A total of 245 patients with ages between 13 and 98 years old and a mean of 45.4 years had extremity AIS scores of 3 or 4. Of these, significantly more men (170 - p< 0.001) suffered this type of injury than women (71). Thirty-six (14.94%) of these patients lost consciousness compared to 205 (85.06%) who did not lose consciousness. The total death rate in this group of patients was 5.39%; 9 (25%) of the 36 patients who lost consciousness and 4 (1.95%) of the 205 who did not lose consciousness died (Fisher exact test: p-value = 0.0001 and relative risk = 12,813 - 95% confidence index: 4,166 to 39,408).
Conclusion:
Loss of consciousness in patients with orthopedic injuries of the extremities is associated to a higher death rate.
Related Concept Videos
Traumatic Brain Injury l: Introduction
Secondary Spinal Cord Injury llI: Pathophysiology
Introduction Cardiac Emergencies
Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation
Decreased Body Temperature
Ischemic Stroke ll: Pathophysiology
