Related Experiment Video
Updated: May 15, 2026

09:11
Use of MRI-ultrasound Fusion to Achieve Targeted Prostate Biopsy
Published on: April 9, 2019
Development of an MRI-compatible device for prostate focal therapy
Jeremy Cepek1, Blaine Chronik, Uri Lindner
1Robarts Research Institute, Western University, London, Canada. jcepek@robarts.ca
Summary
This study introduces a novel MRI-guided device for prostate focal thermal therapy. It enables accurate, in-scanner needle delivery, reducing procedure time and enhancing treatment precision for prostate cancer.
Area of Science:
- Medical Devices
- Oncology
- Radiology
Background:
- Prostate focal thermal therapy requires precise targeting for effective treatment.
- Existing methods for MRI-guided prostate interventions can be time-consuming and complex.
Purpose of the Study:
- To develop and evaluate a novel, manually actuated device for MRI-guided prostate interventions.
- To enable accurate, in-scanner needle delivery for focal thermal therapy, reducing procedure time.
Main Methods:
- A manually actuated mechanical linkage device with optical encoders was designed.
- A custom MR-compatible alignment interface was developed for in-bore targeting.
- Needle targeting accuracy was assessed using gel phantoms.
Main Results:
- The device allows needle delivery to prostate targets without patient removal from the MRI scanner.
- Manual actuation and a compact design reduce system complexity and improve portability.
- Experiments demonstrated a needle targeting accuracy of 2.1 +/- 1.3 mm in gel phantoms.
Conclusions:
- The developed device offers a simpler, more portable, and accurate solution for MRI-guided prostate interventions.
- In-scanner targeting capability significantly reduces procedure time and enhances precision for focal thermal therapy.
- This technology has the potential to improve the efficacy and accessibility of prostate cancer treatments.

