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Streptococcus pseudopneumoniae: an emerging respiratory tract pathogen

J Sariya Mohammadi1, B Dhanashree

  • 1Department of Microbiology, Kasturba Medical College, Manipal University, Mangalore, India.

The Indian Journal of Medical Research
|January 5, 2013
PubMed
Abstract

Insights

Streptococcus pseudopneumoniae was identified in Indian respiratory tract infection samples and showed erythromycin resistance. Accurate identification requires specific tests to differentiate it from Streptococcus pneumoniae.

Area of Science:

  • Medical Microbiology
  • Bacteriology
  • Infectious Diseases

Background:

  • Streptococcus pseudopneumoniae, a Viridans Streptococci member, is linked to chronic obstructive pulmonary disease and respiratory tract infections (RTI).
  • Limited data exists on S. pseudopneumoniae isolation in India.

Purpose of the Study:

  • To isolate S. pseudopneumoniae from clinical samples in India.
  • To determine the drug resistance patterns of S. pseudopneumoniae isolates.

Main Methods:

  • Sputum samples (n=150) from patients with suspected lower respiratory tract infections were cultured.
  • Identification of S. pseudopneumoniae involved assessing capsule absence, bile solubility, and optochin susceptibility under specific atmospheric conditions.
  • Antibiotic susceptibility testing was performed using the disk diffusion method.

Main Results:

  • S. pseudopneumoniae was isolated from 4% of the screened samples.
  • All S. pseudopneumoniae isolates exhibited resistance to erythromycin.
  • Other co-isolated pathogens included Streptococcus pneumoniae, Moraxella catarrhalis, and Klebsiella spp.

Conclusions:

  • S. pseudopneumoniae is present in India and associated with RTIs.
  • Standard laboratory methods may misidentify S. pseudopneumoniae as S. pneumoniae.
  • Accurate differentiation requires optochin susceptibility testing in both 5% CO₂ and ambient air, along with bile solubility tests.

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