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Retinal angiomatous proliferation occurring after radiotherapy.
G De Salvo1, S R Hannan, N James
1Southampton Eye Unit, University Hospital Southampton, Southampton, UK.
Eye (London, England)
|January 5, 2013
Summary
Retinal angiomatous proliferation (RAP)-like lesions can occur after radiation therapy for tumors. Intravitreal Ranibizumab injections effectively treated these radiation-induced ocular conditions.
Area of Science:
- Ophthalmology
- Radiation Oncology
Background:
- Radiation therapy is a common treatment for various tumors.
- Ocular complications following radiotherapy require careful monitoring and understanding.
Observation:
- Two cases of retinal angiomatous proliferation (RAP)-like lesions were identified post-radiation therapy.
- Patients had prior irradiation for lacrimal gland pleomorphic adenoma and vocal cord carcinoma.
- Diagnostic imaging confirmed RAP-like lesions in both individuals.
Findings:
- Intravitreal injections of Ranibizumab were administered to both patients.
- Positive treatment response observed, including improved visual acuity (VA).
- Reduction in intraretinal fluid was noted on optical coherence tomography.
Implications:
- Radiation treatment can induce RAP-like lesions in the retina.
- Consider prior radiotherapy history in patients with idiopathic RAP.
- Ranibizumab shows promise in managing radiation-induced RAP-like lesions.
