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Updated: May 15, 2026

Sensing of Barrier Tissue Disruption with an Organic Electrochemical Transistor
Published on: February 10, 2014
Electrolyte-gated organic field-effect transistor sensors based on supported biotinylated phospholipid bilayer
Maria Magliulo1, Antonia Mallardi, Mohammad Yusuf Mulla
1Dipartimento di Chimica, Università degli Studi di Bari Aldo Moro, Bari, Italy.
Abstract:
Anchored, biotinylated phospholipids forming the capturing layers in an electrolyte-gated organic field-effect transistor (EGOFET) allow label-free electronic specific detection at a concentration level of 10 nM in a high ionic strength solution. The sensing mechanism is based on a clear capacitive effect across the PL layers involving the charges of the target molecules.
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