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Updated: May 15, 2026

Assaying Protein Kinase Activity with Radiolabeled ATP
Published on: May 26, 2017
Physiological functions of protein kinase D in vivo
Kornelia Ellwanger1, Angelika Hausser
1Institute of Cell Biology and Immunology, University of Stuttgart, Allmandring 31, Stuttgart, Germany.
Abstract:
The cellular functions of the serine/threonine protein kinase D (PKD) have been extensively studied within the last decade and distinct roles such as fission of vesicles at the Golgi compartment, coordination of cell migration and invasion, and regulation of gene transcription have been correlated with this kinase family. Here, we highlight the current state of in vivo studies on PKD function with a focus on animal models and discuss the molecular basis of the observed phenotypic characteristics associated with this kinase family.
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