Related Experiment Video
Updated: May 15, 2026

Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies
Published on: February 6, 2019
[Clinical implementation of dose reconstruction and dose-guided intensity modulated radiotherapy for helical
Weirong Yao1, Shouping Xu, Du Lei
1Department of Radiation Oncology, Chinese PLA General Hospital, Beijing, China. yaoweirong2901@126.com
Objective:
To implement dose reconstruction and dose-guided intensity modulated radiotherapy for helical tomotherapy.
Methods:
Dose reconstruction was implemented on adaptive helical tomotherapy with the online megavoltage CT (MVCT) imaging from a patient with nasopharyngeal cancer. The differences of isodose line between actual and planned deposition were analysis in 3D distribution, on which the hot spot and cold spot were lined. The dose delivered to these areas was modulated in later fractions to keep the planned requirement.
Results:
The differences between actual and planned isodose line were shown on the image visually. The modulation to the hot spot and cold spot in later fraction corrected the incorrectly delivered dose to achieve the requirement of primary plan.
Conclusions:
The dose reconstruction and dose-guided intensity modulated radiotherapy can be implemented in adaptive helical tomotherapy.

