Related Experiment Video
Updated: May 15, 2026

09:32
Manufacturing Abdominal Aorta Hydrogel Tissue-Mimicking Phantoms for Ultrasound Elastography Validation
Published on: September 19, 2018
Target setting for elective infra-renal AAA surgery: A single mortality figure?
Kathryn J Griffin1, Sarah J Fleming, Marc A Bailey
1Leeds Vascular Institute, Leeds General Infirmary, Great George Street, Leeds LS1 3EX, UK. kgriffin@doctors.org.uk
Summary
Statistical targets for abdominal aortic aneurysm (AAA) repair mortality are problematic due to natural variability and case-mix issues. Further research is needed for effective national and international performance comparisons.
Area of Science:
- Vascular Surgery
- Health Services Research
- Biostatistics
Background:
- National standards for elective abdominal aortic aneurysm (AAA) repair mortality are set at <6% by the UK NAAASP.
- There is an ongoing aim to reduce elective AAA repair mortality to 3.5% by 2013.
- The statistical validity of these mortality targets requires investigation.
Purpose of the Study:
- To investigate the statistical validity of mortality targets for elective abdominal aortic aneurysm (AAA) repair.
- To analyze data missingness in the National Vascular Database (NVD) for AAA procedures.
- To model the impact of unit size and case-mix on observed mortality rates.
Main Methods:
- Interrogation of the National Vascular Database (NVD) to assess AAA data completeness and geographical variation.
- Utilisation of published data (2006-2008) and funnel plots to illustrate NHS Trust mortality rates.
- Application of a binomial distribution model to calculate mortality variation based on patient volume and a "true" mortality rate of 3.5%.
Main Results:
- The NVD AAA dataset exhibits significant data missingness (median 22%), with higher rates in non-preferred variables.
- Simulated funnel plots show greater 3-year mortality variability in smaller surgical units compared to larger ones.
- Data missingness for preferred clinical variables ranges from 5% to 50%, impacting risk modeling.
Conclusions:
- Sole reliance on a single mortality figure for performance assessment is problematic due to statistical variability and unaddressed case-mix factors.
- Further research into mortality target setting is crucial.
- Developing national strategies and facilitating international comparisons are recommended for improved performance evaluation.