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Radio-active iodine uptake in vitiligo
V Kumar1, V Shankar, S Chaudhary
1Department of Dermatology, Medical College and Hospital, Rohtak, India.
The Journal of Dermatology
|January 1, 1990
Summary
Vitiligo patients often have thyroid issues. This study found half of euthyroid vitiligo patients showed abnormal thyroid function, suggesting a tendency toward hypothyroidism.
Area of Science:
- Endocrinology
- Dermatology
- Autoimmune Disorders
Background:
- Vitiligo and thyroid disease frequently co-occur.
- Understanding the thyroid status in vitiligo patients is crucial.
Purpose of the Study:
- To assess thyroid function in clinically euthyroid vitiligo patients.
- To investigate the association between vitiligo and subclinical thyroid dysfunction.
Main Methods:
- Studied 22 euthyroid vitiligo patients.
- Utilized radioactive iodine uptake assay for thyroid functional assessment.
Main Results:
- Half of the patients exhibited abnormal 24-hour radioactive iodine uptake.
- 90% of those with abnormal uptake showed lower values, indicating a hypothyroid tendency.
Conclusions:
- Subclinical thyroid dysfunction is prevalent in vitiligo.
- This dysfunction may represent an adaptive change in vitiligo patients.