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Updated: May 15, 2026

Evaluation of Antimicrobial Activities of Nanoparticles and Nanostructured Surfaces In Vitro
Published on: April 21, 2023
Evaluation of minimum inhibitory and minimum bactericidal concentration of nano-silver base inorganic anti-microbial
Goda Holla1, Ramakrishna Yeluri, Autar Krishen Munshi
1Department of Pedodontics and Preventive Dentistry, Kanti Devi Denta College and Hospital, Mathura, Uttar Pradesh, India.
Objective:
We attempted to find the possibility of determining the minimum inhibitory concentration and minimum bactericidal concentration needed for nano-silver base inorganic anti-microbial agent (Novaron(®) AG 300, AG 1100) against Streptococcus mutans in vitro using broth dilution assay.
Materials And Methods:
An ampoule of freeze-dried S. mutans NCTC reference strain was revived, and the colony-forming units (CFU) were calculated. The MIC and MBC was determined by broth dilution assay using different concentrations of Novaron(®) AG 300 and Novaron(®) AG 1100 against 1 × 10(5) CFU/ml of S. mutans.
Results:
The MIC and MBC of Novaron(®) AG 300 and Novaron(®) AG 1100 against S. mutans were found to be 40 μg/ml.
Conclusions:
Novaron(®) has anti-bacterial effect against S. mutans. Further studies are needed to explore the applicability of these silver-supported anti- microbial agents in clinical dentistry.
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