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High-throughput Screening and Biosensing with Fluorescent C. elegans Strains
Published on: May 19, 2011
A turn-on fluorescent sensor for the discrimination of cystein from homocystein and glutathione
Li-Ya Niu1, Ying-Shi Guan, Yu-Zhe Chen
1Key Laboratory of Photochemical Conversion and Optoelectronic Materials, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing, 100190, PR China.
Abstract:
We report a turn-on fluorescent sensor based on nitrothiophenolate boron dipyrromethene (BODIPY) derivatives for the discrimination of cystein (Cys) from homocystein (Hcy) and glutathione (GSH). The sensor was applied for detection of Cys in living cells.

