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Software tools for glycan profiling.

Chuan-Yih Yu¹, Anoop Mayampurath, Haixu Tang

¹School of Informatics and Computing, Indiana University, Bloomington, IN, USA.

Methods in Molecular Biology (Clifton, N.J.)

|January 9, 2013

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Three new software tools, Cartoonist, GlycoWorkbench, and MultiGlycan, aid in N-glycan profiling of biological samples. Their usability and performance are detailed using real-world glycan profiling data.

Area of Science:

Biochemistry
Computational Biology
Glycomics

Background:

N-glycan profiling is crucial for understanding biological processes.
Analyzing complex biological samples presents significant challenges.

Purpose of the Study:

To introduce three novel software tools: Cartoonist, GlycoWorkbench, and MultiGlycan.
To provide detailed instructions for utilizing these tools in N-glycan analysis.
To demonstrate the performance of these tools with real-world data.

Main Methods:

Development and application of Cartoonist software.
Utilisation of GlycoWorkbench for glycan analysis.
Implementation of MultiGlycan for complex sample profiling.

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A Quantitative Glycomics and Proteomics Combined Purification Strategy

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Glycomics-Guided Glycoproteomics Facilitates Comprehensive Profiling of the Glycoproteome in Complex Tumor Microenvironments

Glycomics-Guided Glycoproteomics Facilitates Comprehensive Profiling of the Glycoproteome in Complex Tumor Microenvironments

Published on: February 7, 2025

A Quantitative Glycomics and Proteomics Combined Purification Strategy

A Quantitative Glycomics and Proteomics Combined Purification Strategy

Published on: March 8, 2016

Main Results:

Successful N-glycan profiling of complex biological samples was achieved.
The software tools demonstrated effective performance in data analysis.
User-friendly instructions facilitate the application of these tools.

Conclusions:

Cartoonist, GlycoWorkbench, and MultiGlycan are valuable additions to glycomics research.
These tools enhance the efficiency and accuracy of N-glycan profiling.
The provided data confirms the practical utility of the software.