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Related Concept Videos

Somatosensation01:33

Somatosensation

The somatosensory system relays sensory information from the skin, mucous membranes, limbs, and joints. Somatosensation is more familiarly known as the sense of touch. A typical somatosensory pathway includes three types of long neurons: primary, secondary, and tertiary. Primary neurons have cell bodies located near the spinal cord in groups of neurons called dorsal root ganglia. The sensory neurons of ganglia innervate designated areas of skin called dermatomes.
Healing II: Complications01:24

Healing II: Complications

Complications during healing arise when tissue repair is altered by local or systemic factors. These changes involve abnormal collagen deposition, altered biomechanics, and reduced vascular supply, impairing restoration of normal structure and function.Loss of FunctionScar tissue differs significantly from the original tissue it replaces. In the skin, fibrosis lacks adnexal structures such as hair follicles, sebaceous glands, and sweat glands. Their absence reduces tactile sensitivity, impairs...
Alterations in Muscle Tone ll01:12

Alterations in Muscle Tone ll

Alterations in muscle tone are common manifestations of neurological disorders and reflect dysfunction within different nervous system regions. Spasticity, paratonia, and dystonia represent distinct forms of hypertonia, each with unique mechanisms, clinical features, and diagnostic importance.CharacteristicsSpasticity happens from upper motor neuron lesions and is characterized by velocity-dependent resistance to passive movement. Clinical features include:Exaggerated deep tendon reflexesClonus...
Cushing Syndrome I: Introduction01:26

Cushing Syndrome I: Introduction

Cushing syndrome refers to the collection of clinical manifestations that arise when tissues are exposed to excessive amounts of cortisol or cortisol-like medications over an extended period. Cortisol, a glucocorticoid produced by the adrenal cortex, regulates metabolism, immune responses, and the body’s adaptation to stress. When its concentration remains chronically elevated, these physiological pathways become dysregulated, resulting in the characteristic features of the syndrome.Exogenous...
Major Somatic Sensory Pathways01:28

Major Somatic Sensory Pathways

Sensory impulses related to touch, pressure, vibration, and proprioception from various body parts, such as the limbs, trunk, neck, and posterior head, travel to the cerebral cortex through the posterior column-medial lemniscus pathway. The pathway’s name derives from the two white-matter tracts that convey the impulses: the spinal cord's posterior column and the brainstem's medial lemniscus. First-order sensory neurons extend their axons into the spinal cord, forming the posterior columns...
Positive Symptoms of Schizophrenia: Hallucinations and Delusions01:30

Positive Symptoms of Schizophrenia: Hallucinations and Delusions

Schizophrenia is a complex mental health disorder that can manifest with various positive symptoms, including thought, movement, and behavior disorders. These symptoms significantly disrupt cognitive and motor functions, leading to profound effects on an individual's ability to engage with the world.
Thought Disorders
Disorganized and unusual thought processes mark thought disorders in schizophrenia. One key feature is disorganized speech, where an individual's conversation includes loosely...

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Related Experiment Video

Updated: May 15, 2026

Fiber Connections of the Supplementary Motor Area Revisited: Methodology of Fiber Dissection, DTI, and Three Dimensional Documentation
16:23

Fiber Connections of the Supplementary Motor Area Revisited: Methodology of Fiber Dissection, DTI, and Three Dimensional Documentation

Published on: May 23, 2017

Somatization severity associated with postero-medial complex structures.

Erwin Lemche1, Vincent P Giampietro, Michael J Brammer

  • 1Section of Cognitive Neuropsychiatry, Institute of Psychiatry, King's College Medical School, London SE5 8AF, United Kingdom. erwin.lemche@kcl.ac.uk

Scientific Reports
|January 10, 2013
PubMed
Summary
This summary is machine-generated.

This study explored the brain mechanisms behind somatisation, finding links between symptom severity and brain activity in regions like the precuneus and thalamus. These findings suggest emotional states influence how the brain processes bodily sensations.

Related Experiment Videos

Last Updated: May 15, 2026

Fiber Connections of the Supplementary Motor Area Revisited: Methodology of Fiber Dissection, DTI, and Three Dimensional Documentation
16:23

Fiber Connections of the Supplementary Motor Area Revisited: Methodology of Fiber Dissection, DTI, and Three Dimensional Documentation

Published on: May 23, 2017

Area of Science:

  • Neuroscience
  • Psychiatry
  • Psychophysiology

Background:

  • Somatisation is common in psychiatric disorders but its cerebral mechanisms are poorly understood.
  • The influence of emotional states on somatisation and its neural correlates require investigation.

Purpose of the Study:

  • To investigate the relationship between somatisation severity, neural effective connectivity, and autonomic responses.
  • To identify brain regions involved in the processing of emotional facial expressions and their link to somatisation.

Main Methods:

  • Used functional magnetic resonance imaging (fMRI) with a fast implicit emotional faces paradigm.
  • Measured skin conductance levels (SCL) concurrently with fMRI.
  • Correlated self-reported somatisation severity (SOMS-2) with neural activity and effective connectivity.

Main Results:

  • Somatisation severity correlated with neural activity in the anterior ventral precuneus (BA7) for both happy and sad emotions.
  • The posterior cingulate gyrus (PCC, BA23) showed correlation in the sad condition, and the anteromedial thalamus in the happy condition.
  • Effective connectivity analyses linked these brain regions to peripheral autonomic responses.

Conclusions:

  • Neural activity in specific brain regions, including the precuneus, PCC, and thalamus, is associated with somatisation severity.
  • Emotional states appear to modulate neural processing related to somatisation.
  • Findings provide insights into the brain bases of somatisation and its connection to emotional processing.