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Targeted Cancer Therapies

Targeted Cancer Therapies

The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against specific...

Targeted Cancer Therapies

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mTOR Signaling and Cancer Progression

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mTOR Signaling and Cancer Progression

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Inhibition of Cdk Activity

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Related Experiment Video

Updated: May 15, 2026

Using Mouse Mammary Tumor Cells to Teach Core Biology Concepts: A Simple Lab Module

Using Mouse Mammary Tumor Cells to Teach Core Biology Concepts: A Simple Lab Module

Published on: June 18, 2015

Cancer-linked targets modulated by curcumin.

Noor Hasima¹, Bharat B Aggarwal

¹Cytokine Research Laboratory, Department of Experimental Therapeutics, The University of Texas MD Anderson Cancer Center Houston, Texas, 77030, United States ; Institute Science Biology, Faculty of Science, University of Malaya 50603 Kuala Lumpur, Malaysia.

International Journal of Biochemistry and Molecular Biology

|January 10, 2013

Summary

Curcumin, a natural compound from turmeric, shows potential as a safe and affordable cancer treatment. It targets multiple cancer pathways, unlike expensive single-target drugs, but more clinical trials are needed.

Keywords:

Curcumin cancer targets

Related Experiment Videos

Last Updated: May 15, 2026

Using Mouse Mammary Tumor Cells to Teach Core Biology Concepts: A Simple Lab Module

Using Mouse Mammary Tumor Cells to Teach Core Biology Concepts: A Simple Lab Module

Published on: June 18, 2015

Area of Science:

Oncology
Natural Compounds
Cancer Biology

Background:

Cancer incidence is projected to double, with current treatments focusing on single targets and primary tumors.
Existing targeted therapies often lack specificity, cause significant side effects, and are prohibitively expensive.
Over 90% of cancer deaths result from metastasis, yet most drug development targets the primary tumor.

Purpose of the Study:

To explore the potential anticancer properties of curcumin, a safe and low-cost compound derived from turmeric (Curcuma longa).
To evaluate curcumin's ability to modulate multiple cell signaling pathways involved in cancer progression.

Main Methods:

Review of existing research on curcumin's biological activities.
Analysis of curcumin's effects on cell signaling pathways related to cancer.

Main Results:

Curcumin demonstrates the ability to selectively modulate multiple cell signaling pathways.
These pathways are critical for inflammation, cancer cell survival, growth, invasion, angiogenesis, and metastasis.
Curcumin is known for its safety and affordability.

Conclusions:

Curcumin presents a promising, multi-targeted approach to cancer therapy.
Its safety profile and low cost make it an attractive alternative or adjunct to current treatments.
Further clinical trials are essential to validate curcumin's efficacy in cancer patients.