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Updated: May 15, 2026
10:33
Primed Mycobacterial Uveitis (PMU) as a Model for Post-Infectious Uveitis
Published on: December 17, 2021
[Zoledronic acid-based uveitis: a case report and a bibliography review]
Mario Albani-Campanario1, Gerardo Buendía-Díaz, María de Lourdes Flores-Islas
1Red Crea. albani@redcrea.com.mx
Ginecologia Y Obstetricia De Mexico
|January 11, 2013
Summary
Bisphosphonates treat osteoporosis by inhibiting bone resorption but can cause side effects. This report details an exceptional case of zoledronic acid-induced uveitis in a postmenopausal patient.
Area of Science:
- Ophthalmology
- Endocrinology
- Pharmacology
Background:
- Osteoporosis and osteopenia are common in postmenopausal women.
- Bisphosphonates are a primary treatment, inhibiting bone resorption.
- Gastrointestinal issues are common bisphosphonate side effects.
Observation:
- A 58-year-old patient developed uveitis symptoms.
- The patient was undergoing treatment with zoledronic acid.
- Uveitis is an uncommon side effect of bisphosphonate therapy.
Findings:
- Zoledronic acid was identified as the likely cause of the patient's uveitis.
- This adverse drug reaction is exceptionally rare for this specific bisphosphonate.
- Ocular inflammation can be a serious complication of bisphosphonate treatment.
Implications:
- Clinicians should be aware of rare ocular side effects associated with bisphosphonates.
- Prompt diagnosis and management of uveitis are crucial in patients on bisphosphonate therapy.
- Further research may be needed to understand the mechanism of bisphosphonate-induced uveitis.
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