[The diagnostic value of serum alveomucin test in diseases with lungs affection]

The study was organized to determine the diagnostic value of concentration of blood serum alveo-mucin as a marker of lesion of lung tissue in patients with community-acquired pneumonia and hemorrhagic fever with renal syndrome. The sampling included 86 patients with community-acquired pneumonia and 97 patients with hemorrhagic fever with renal syndrome. The patients with community-acquired pneumonia were divided in three groups according severity of disease course: slight form, medium-severe form and severe form of disease. The group of patients with medium-severe form of hemorrhagic fever with renal syndrome was divided on two groups depending on clinical roentgenologic pattern: with and without pathology of lungs. The high concentration of alveomucin at the day of hospitalization is typical for patients both with community-acquired pneumonia and with roentgenologically approved lungs affection in case of hemorrhagic fever with renal syndrome in comparison with patients with hemorrhagic fever with renal syndrome without affection of lung tissue (p=0.046). The concentration of alveomucin higher than 47.2 U/ml is established in 86% of patients with community-acquired pneumonia and affection of lung in case of hemorrhagic fever with renal syndrome and in 12% of patients with hemorrhagic fever with renal syndrome without affection of lungs (chi2=0.58 with Yeats equalization, p=0.44).