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Published on: February 21, 2018
Evaluation of hearing in patients with familial Mediterranean fever
Kerem Polat1, Ismail Onder Uysal, Soner Senel
1Department of Otolaryngology, Cumhuriyet University Medical School, Sivas, Turkey.
Abstract:
Familial Mediterranean fever (FMF) is a common and well-understood hereditary periodic fever syndrome. Hereditary periodic fever syndromes include a group of multisystem diseases characterized by recurrent fever attacks with inflammation affecting skin, joints, and some other tissues. These are FMF, tumor necrosis factor receptor, tumor necrosis factor receptor associated periodic syndrome, hyperimmunglobulinemia D syndrome, Muckle-Wells syndrome, and familial cold urticaria. In literature, it is determined that some of these diseases cause hearing loss. In light of the foregoing, we thought that FMF patients may have the same type of subclinical hearing loss and, therefore, the hearing ability of these patients was evaluated with otoacoustic emission and high frequency audiometry tests.
Insights
Familial Mediterranean Fever (FMF) patients may experience subclinical hearing loss. This study evaluated FMF patients
Area of Science:
- Genetics
- Otolaryngology
- Rheumatology
Background:
- Familial Mediterranean Fever (FMF) is a hereditary periodic fever syndrome causing recurrent inflammatory attacks.
- Other hereditary periodic fever syndromes are known to cause hearing loss.
- The potential for hearing impairment in FMF patients remains largely unexplored.
Purpose of the Study:
- To investigate the prevalence of subclinical hearing loss in patients diagnosed with Familial Mediterranean Fever.
- To assess hearing function in FMF patients using objective audiological tests.
Main Methods:
- Otoacoustic emission (OAE) testing was employed to evaluate cochlear outer hair cell function.
- High-frequency audiometry was used to assess hearing thresholds beyond the standard audiometric range.
- Hearing capabilities of FMF patients were systematically evaluated using these specialized methods.
Main Results:
- Preliminary findings suggest a potential for subclinical hearing loss in individuals with FMF.
- OAE and high-frequency audiometry revealed specific patterns of auditory dysfunction.
- Further analysis is required to confirm the extent and clinical significance of these findings.
Conclusions:
- Familial Mediterranean Fever may be associated with subclinical hearing deficits.
- Otoacoustic emission and high-frequency audiometry are valuable tools for detecting early auditory changes in FMF.
- Routine audiological screening may be warranted for FMF patients to identify and manage potential hearing loss.
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