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Updated: May 15, 2026
07:24
Intravitreal Injection and Quantitation of Infection Parameters in a Mouse Model of Bacterial Endophthalmitis
Published on: February 6, 2021
Endophthalmitis caused by Acinetobacter baumanni: a case series.
R Roy1, P Panigrahi, J Malathi
1Vitreo Retina Services, Aditya Birla Sankara Nethralaya, Kolkata, West Bengal, India. rayrupak@gmail.com
Eye (London, England)
|January 12, 2013
Summary
Acinetobacter baumanni endophthalmitis is rare and has poor outcomes. Ciprofloxacin shows 100% sensitivity, making it a potential first-line treatment for this serious eye infection.
Area of Science:
- Ophthalmology
- Infectious Diseases
- Microbiology
Background:
- Endophthalmitis, a severe intraocular infection, can lead to vision loss.
- Acinetobacter baumanni is an opportunistic pathogen increasingly recognized in healthcare-associated infections.
Observation:
- This study analyzed four cases of Acinetobacter baumanni endophthalmitis in Eastern India (2009-2011).
- Cases were predominantly post-cataract surgery or post-traumatic.
- Acinetobacter baumanni was isolated from vitreous samples in all cases.
Findings:
- All isolates were 100% sensitive to ciprofloxacin but resistant to ceftazidime.
- Visual and anatomical outcomes were generally poor, with one patient achieving 20/200 vision.
Implications:
- Acinetobacter baumanni is a rare but devastating cause of endophthalmitis.
- Ciprofloxacin is a promising first-line intravitreal antibiotic for Acinetobacter baumanni endophthalmitis.
- Early diagnosis and targeted antibiotic therapy are crucial for managing this condition.
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