Related Experiment Video

Updated: May 15, 2026

A Mouse 5/6th Nephrectomy Model That Induces Experimental Uremic Cardiomyopathy
07:52

A Mouse 5/6th Nephrectomy Model That Induces Experimental Uremic Cardiomyopathy

Published on: November 7, 2017

Cardiovascular mortality in dialysis patients

Ashraf Al-Dadah1, Jad Omran, Maen B Nusair

  • 1Cardiovascular Medicine Division, University of Missouri-Columbia, Columbia, Missouri 65212, USA.

Advances in Peritoneal Dialysis. Conference on Peritoneal Dialysis
|January 15, 2013
PubMed

Insights

Cardiovascular diseases are the leading cause of death for dialysis patients, who face unique uremia-associated risks. Limited clinical trial data hinders understanding of effective treatments for these patients undergoing peritoneal dialysis or hemodialysis.

Area of Science:

  • Nephrology
  • Cardiology
  • Internal Medicine

Background:

  • Cardiovascular diseases (CVD) are the primary cause of mortality in patients undergoing dialysis.
  • Dialysis patients face traditional cardiac risk factors alongside unique uremia-associated risks.
  • Limited data exists on the efficacy of interventions for cardiovascular outcomes in this population.

Purpose of the Study:

  • To review major cardiovascular problems in dialysis patients.
  • To examine the impact of these cardiovascular problems on survival.
  • To discuss the effectiveness of therapeutic strategies for cardiovascular outcomes in dialysis patients.

Main Methods:

  • This is a review article.
  • It synthesizes existing literature on cardiovascular issues in dialysis patients.
  • It analyzes data on therapeutic interventions where available.

Main Results:

  • Cardiovascular diseases significantly impact survival rates in dialysis patients.
  • Specific uremic factors contribute to heightened cardiac risk.
  • Evidence for routine pharmacologic and procedural interventions is scarce.

Conclusions:

  • Addressing cardiovascular disease is critical for improving survival in dialysis patients.
  • Further research and clinical trials are needed to establish effective treatments.
  • Understanding and managing uremia-specific cardiac risks is essential.

More Related Videos

Measurement of Tissue Oxygenation Using Near-Infrared Spectroscopy in Patients Undergoing Hemodialysis04:36

Measurement of Tissue Oxygenation Using Near-Infrared Spectroscopy in Patients Undergoing Hemodialysis

Published on: October 2, 2020

Related Concept Videos

Hemodialysis II: Procedure and Complications01:24

Hemodialysis II: Procedure and Complications

DialyzersA hemodialysis (HD) dialyzer is a plastic cartridge containing thousands of parallel hollow fibers, which serve as semipermeable membranes. These fibers are typically made from cellulose-based or other synthetic materials. During HD, blood is pumped into the top of the cartridge and distributed among these fibers. Simultaneously, dialysis fluid, known as dialysate, is introduced into the bottom of the cartridge, bathing the outside of the fibers. Across the semipermeable membrane,...
Dialysis01:27

Dialysis

Renal failure occurs when the kidneys lose their ability to filter waste products from the blood effectively. It can be classified into two types: acute renal failure (ARF) and chronic renal failure (CRF).
Acute kidney injury develops suddenly and can be caused by pre-renal causes (e.g., hypovolemia, shock), intrinsic renal causes (e.g., acute tubular necrosis), or post-renal causes (e.g., urinary obstruction). In contrast, chronic renal failure progresses gradually over time and is often...
Dialysis01:15

Dialysis

Dialysis is a diffusion-based purification process that separates analyte molecules from a complex matrix. This is accomplished by allowing molecules in the solution to pass through a semipermeable membrane into a liquid on the other side. The membrane is usually made of cellulose acetate or cellulose nitrate, and the second liquid must be miscible with the solution. Ions (e.g., chloride or sodium) or organic molecules (e.g., glucose) can pass through the membrane pores, which generally have...
Hemodialysis III: Nursing Management01:25

Hemodialysis III: Nursing Management

The nursing management of a patient undergoing hemodialysis includes several critical steps, starting with a thorough assessment before the procedure.Before the Hemodialysis ProcedureFirst, record the patient's vital signs—blood pressure, heart rate, respiratory rate, and temperature—to establish a baseline. This baseline is essential for detecting conditions such as hypotension that could impact the patient's response to dialysis. Document the patient's pre-dialysis weight, as this measurement...
Hemodialysis I: Introduction01:25

Hemodialysis I: Introduction

Hemodialysis (HD) is a medical treatment that artificially removes waste products, excess fluids, and toxins from the blood when the kidneys are no longer able to perform these functions effectively. In this process, blood is filtered through a semipermeable membrane, allowing for the selective removal of waste while preserving necessary components like blood cells and proteins. Hemodialysis is typically performed in patients with end-stage renal disease (ESRD) or severe kidney...
Chronic Kidney Disease II: Clinical Manifestations01:24

Chronic Kidney Disease II: Clinical Manifestations

Chronic Kidney Disease (CKD) progressively impairs multiple body systems due to the accumulation of uremic toxins, which disrupt cellular functions across various organs.Neurologic symptomsNeurologic symptoms often arise early in CKD, as uremic toxin buildup drives changes in cognitive and motor functions. Patients frequently experience fatigue, headache, confusion, difficulty concentrating, and, in severe cases, seizures. Peripheral neuropathy commonly manifests as burning sensations in the...