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Related Experiment Video

Updated: May 15, 2026

Correction of Presbyopia by Monocular Bi-Aspheric Ablation Profile

Published on: September 20, 2024

Corneal higher order aberrations after myopic wavefront-optimized ablation.

David Smadja¹, Marcony R Santhiago, Glauco R Mello

¹Cole Eye Institute, Cleveland Clinic Foundation, Refractive Surgery Department, Cleveland, OH, USA. davidsmadj@hotmail.fr

Journal of Refractive Surgery (Thorofare, N.J. : 1995)

|January 15, 2013

Summary

This summary is machine-generated.

Wavefront-optimized LASIK increased corneal higher order aberrations (HOAs) in myopic eyes, particularly with higher corrections. This suggests current algorithms may need refinement for better visual outcomes.

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Last Updated: May 15, 2026

Correction of Presbyopia by Monocular Bi-Aspheric Ablation Profile

Published on: September 20, 2024

$Comparison of Agreement and Accuracy using Binocular Wavefront Optometer with Autorefractor and Phoropter$

Comparison of Agreement and Accuracy using Binocular Wavefront Optometer with Autorefractor and Phoropter

Published on: September 16, 2025

Area of Science:

Ophthalmology
Optometry
Corneal Surgery

Background:

Laser-assisted in situ keratomileusis (LASIK) is a common refractive surgery.
Wavefront-optimized ablation aims to minimize induced aberrations.
Corneal higher order aberrations (HOAs) can impact visual quality.

Purpose of the Study:

To analyze induced corneal HOAs after wavefront-optimized myopic LASIK.
To investigate the relationship between myopia severity and HOA induction.
To evaluate the effectiveness of wavefront-optimized ablation in preserving corneal optics.

Main Methods:

Sixty-four myopic eyes underwent wavefront-optimized myopic LASIK.
Eyes were grouped by spherical equivalent (SE): low, moderate, and high myopia.
Corneal HOAs, spherical aberrations, and coma were measured using dual Scheimpflug imaging pre- and post-surgery.

Main Results:

Overall increase in total corneal HOAs (0.18±0.18 μm, P<.01).
Significant induction of positive spherical aberration (0.27±0.25 μm, P<.001).
HOA induction was not significant in the low myopia group (P=.85).

Conclusions:

Wavefront-optimized LASIK significantly induced corneal HOAs despite design goals.
Induced HOA magnitude correlated with the intended refractive correction.
Corneal wavefront data is valuable for refining laser ablation algorithms.