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Updated: May 15, 2026

Standardized Histomorphometric Evaluation of Osteoarthritis in a Surgical Mouse Model
Published on: May 6, 2020
Imaging of osteoarthritis
Ali Guermazi1, Daichi Hayashi, Felix Eckstein
1Department of Radiology, Boston University School of Medicine, Boston, MA 02118, USA. guermazi@bu.edu
Osteoarthritis (OA) is a common elderly joint disorder lacking effective treatments. This review details imaging techniques like radiography and MRI for diagnosing and monitoring knee OA, highlighting recent advancements.
Area of Science:
- Orthopedics
- Radiology
- Rheumatology
Background:
- Osteoarthritis (OA) is the most common joint disease affecting the elderly population.
- Currently, no definitive cure exists for OA, making early diagnosis and monitoring crucial.
- Accurate assessment of synovial joint structures is vital for OA management.
Purpose of the Study:
- To review the roles and limitations of various imaging modalities in the diagnosis, prognosis, and follow-up of knee osteoarthritis.
- To discuss recent research developments and evidence in OA imaging published since 2008.
Main Methods:
- Review of conventional radiography and magnetic resonance (MR) imaging.
- Consideration of ultrasonography, nuclear medicine, computed tomography (CT), and CT/MR arthrography.
- Emphasis on knee OA and literature published post-2008.
Main Results:
- Conventional radiography and MR imaging are key modalities for evaluating knee OA.
- Other techniques like ultrasonography and CT arthrography offer complementary information.
- Recent advancements have improved the diagnostic and prognostic capabilities of OA imaging.
Conclusions:
- Imaging plays a critical role in the clinical practice and research of knee OA.
- A comprehensive understanding of different imaging modalities is essential for effective OA management.
- Ongoing research continues to refine imaging techniques for better OA outcomes.
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