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Related Experiment Video

Updated: May 15, 2026

Modeling Osteosarcoma Using Li-Fraumeni Syndrome Patient-derived Induced Pluripotent Stem Cells

Modeling Osteosarcoma Using Li-Fraumeni Syndrome Patient-derived Induced Pluripotent Stem Cells

Published on: June 13, 2018

Dermatofibrosarcoma protuberans in a child: a case report.

Prashant Goyal¹, Shelly Sehgal, Sompal Singh

¹Department of Pathology, Swami Dayanand Hospital, Shahdara, New Delhi 110095, India.

Case Reports in Dermatological Medicine

|January 15, 2013

Summary

Dermatofibrosarcoma protuberans (DFSP) is a rare skin neoplasm in children, often misdiagnosed. Early recognition and complete surgical excision are crucial for effective management and preventing recurrence in pediatric patients.

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Last Updated: May 15, 2026

Modeling Osteosarcoma Using Li-Fraumeni Syndrome Patient-derived Induced Pluripotent Stem Cells

Modeling Osteosarcoma Using Li-Fraumeni Syndrome Patient-derived Induced Pluripotent Stem Cells

Published on: June 13, 2018

Area of Science:

Pediatric Oncology
Dermatopathology
Surgical Oncology

Background:

Dermatofibrosarcoma protuberans (DFSP) is an intermediate-grade soft tissue neoplasm originating in the dermis.
While typically occurring in adults, DFSP can rarely manifest in infants and children.
Diagnosis in pediatric patients is challenging due to rarity, varied appearance, and potential for unusual presentations.

Purpose of the Study:

To highlight the diagnostic challenges of pediatric Dermatofibrosarcoma protuberans.
To emphasize the importance of timely and complete surgical management.
To underscore the need for increased awareness of this rare childhood neoplasm.

Main Methods:

Case presentation of a five-year-old boy with a forehead lesion.
Initial diagnosis suggested by Fine Needle Aspiration Cytology (FNAC).
Definitive diagnosis confirmed via histopathological examination and subsequent wide margin reexcision surgery.

Main Results:

Histopathology confirmed Dermatofibrosarcoma protuberans (DFSP) in a pediatric patient.
The patient experienced a recurrence after initial treatment due to lost follow-up and presumed incomplete excision.
Delayed treatment and incomplete excision contributed to the unfavorable outcome.

Conclusions:

Pediatric Dermatofibrosarcoma protuberans (DFSP) is rare and diagnostically difficult.
Delayed treatment and incomplete excision are common issues in childhood DFSP.
Prompt recognition and appropriate surgical management are essential for managing this uncommon pediatric neoplasm.