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Updated: May 15, 2026

Erosion Identification in Metacarpophalangeal Joints in Rheumatoid Arthritis using High-Resolution Peripheral Quantitative Computed Tomography
Published on: October 6, 2023
Muehrcke lines associated to active rheumatoid arthritis
Mario Alfredo Chávez-López1, Francisco Javier Arce-Martínez, Adolfo Tello-Esparza
1Department of Rheumatology, Centenario Hospital Miguel Hidalgo, Aguascalientes, México. drmariochavez@yahoo.com
Nail changes like Muehrcke lines can indicate systemic diseases. This case highlights an unusual association between Muehrcke lines and active rheumatoid arthritis, aiding in diagnosis.
Area of Science:
- Dermatology
- Rheumatology
- Internal Medicine
Background:
- Nail examination is crucial for diagnosing systemic diseases.
- Transverse nail discolorations, including Muehrcke lines, have diverse etiologies.
- Rheumatic diseases are a less common cause of Muehrcke lines.
Observation:
- Muehrcke lines are transverse nail bands of leukonychia striata.
- These lines are unspecific, with approximately 70 known causes.
- Cancer treatment is a common cause, while rheumatic diseases are less frequent.
Findings:
- This case report details an unusual presentation of Muehrcke lines.
- The observed Muehrcke lines were associated with active rheumatoid arthritis.
- This association is uncommon in clinical practice.
Implications:
- Recognizing Muehrcke lines can prompt investigation into underlying conditions.
- This case expands the differential diagnosis for Muehrcke lines.
- Early detection of rheumatoid arthritis through nail findings may improve patient outcomes.
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