Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Imaging Studies for Cardiovascular System V: CT

Imaging Studies for Cardiovascular System V: CT

Cardiac computed tomography (CT) scanning is an advanced cardiac imaging technique that utilizes CT technology, with or without intravenous (IV) contrast, to produce accurate cross-sectional virtual slices of specific areas of the heart, coronary circulation, and major blood vessels such as the aorta, pulmonary veins, and arteries. The computer processes these slices to generate three-dimensional images. Multidetector CT (MDCT) is a rapid form of CT scanning that captures multiple slices...

Acute Coronary Syndrome III: Diagnostic Studies

Acute Coronary Syndrome III: Diagnostic Studies

Diagnosing acute coronary syndrome or ACS begins with a thorough patient history. Notable symptoms include central, crushing chest pain radiating to the left arm, neck, jaw, or back, along with shortness of breath, sweating (diaphoresis), nausea, vomiting, dizziness, and palpitations.It is crucial to note any history of cardiac illnesses and assess risk factors, including age, gender, smoking, hypertension, diabetes, hyperlipidemia, and a sedentary lifestyle.During physical examination, vital...

Mitral Stenosis II: Clinical features and Diagnostic Tests

Mitral Stenosis II: Clinical features and Diagnostic Tests

Mitral stenosis is a heart condition in which the mitral valve, which allows blood to flow from the left atrium to the left ventricle, becomes narrowed or stenotic. This narrowing hinders blood flow and leads to clinical symptoms requiring specific medical evaluations and management strategies. The following overview outlines the clinical symptoms, assessments, diagnostic findings, prevention methods, and treatments for mitral stenosis.Clinical ManifestationsDyspnea (shortness of breath): This...

Cardiac Catheterization III: Left Heart Catheterization

Cardiac Catheterization III: Left Heart Catheterization

Left heart catheterization is an invasive diagnostic procedure used to evaluate the function and structure of the left side of the heart. It is generally performed to diagnose and treat cardiovascular conditions such as valve abnormalities, coronary artery disease, and congenital heart defects.Diagnostic and therapeutic purposesLeft heart catheterization serves various diagnostic and therapeutic purposes, including:Assessing coronary artery bypass grafts.Evaluating coronary artery disease in...

Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT

Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT

Calcium-Scoring CT ScanA calcium-scoring CT scan, also known as coronary artery calcium (CAC) scan, detects calcium deposits in the coronary arteries. This test assesses the risk of coronary artery disease (CAD), which can lead to cardiovascular events such as angina, heart failure, and sudden cardiac arrest.A calcium-scoring CT scan is generally recommended for individuals at intermediate risk of CAD without symptoms. It includes:Men aged 40-75 and women aged 50-75: Especially those with a...

Aortic Regurgitation II: Clinical Features and Diagnostic Tests

Aortic Regurgitation II: Clinical Features and Diagnostic Tests

Aortic valve regurgitation (AR) occurs when the aortic valve fails to close properly, allowing blood to flow backward from the aorta into the left ventricle. This backflow can result in two distinct clinical presentations: acute and chronic AR, each characterized by its own set of symptoms and physical findings.Acute Aortic RegurgitationAcute AR presents with a sudden onset of severe symptoms. Patients typically experience profound dyspnea (shortness of breath), chest pain, and signs of left...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Metal-ruthenium complex based on dipyridylamine group as membrane-active antibacterial agent effectively decrease the development of drug-resistance on Staphylococcus aureus.

Journal of inorganic biochemistry·2023

Same author

IFNγ-Producing B Cells Play a Regulating Role in Infection-Mediated Inhibition of Allergy.

Biology·2023

Same author

Synthesis of hierarchically porous zirconium-based metal-organic framework@silica core-shell stationary phase through etching strategy for liquid chromatography.

Journal of chromatography. A·2023

Same author

Lumican silencing ameliorates β-glycerophosphate-mediated vascular smooth muscle cell calcification by attenuating the inhibition of APOB on KIF2C activity.

Open medicine (Warsaw, Poland)·2023

Same author

N6-methyladenosine-induced METTL1 promotes tumor proliferation via CDK4.

Biological chemistry·2023

Same author

Circ_0005736 promotes tenogenic differentiation of tendon-derived stem cells through the miR-636/MAPK1 axis.

Journal of orthopaedic surgery and research·2023

Search research articles

Related Experiment Video

Updated: May 15, 2026

Cardiac Magnetic Resonance for the Evaluation of Suspected Cardiac Thrombus: Conventional and Emerging Techniques

Cardiac Magnetic Resonance for the Evaluation of Suspected Cardiac Thrombus: Conventional and Emerging Techniques

Published on: June 11, 2019

Computed tomography for detecting left atrial thrombus: a meta-analysis.

Xiaosan Wu¹, Congxia Wang, Chunyan Zhang

¹Department of Cardiovascular Medicine, Second Affiliated Hospital of Medical School, Xi'an Jiaotong University, Shaanxi, China.

Archives of Medical Science : AMS

|January 16, 2013

Summary

Computed tomography (CT) accurately detects left atrial and appendage thrombus, a complication of atrial fibrillation. This noninvasive imaging method shows high sensitivity and specificity, making it a valuable alternative to transesophageal echocardiography.

Keywords:

computed tomography left atrial thrombus meta-analysis transesophageal echocardiography

More Related Videos

Echocardiographic Evaluation of Atrial Communications before Transcatheter Closure

Echocardiographic Evaluation of Atrial Communications before Transcatheter Closure

Published on: February 8, 2022

Related Experiment Videos

Last Updated: May 15, 2026

Cardiac Magnetic Resonance for the Evaluation of Suspected Cardiac Thrombus: Conventional and Emerging Techniques

Cardiac Magnetic Resonance for the Evaluation of Suspected Cardiac Thrombus: Conventional and Emerging Techniques

Published on: June 11, 2019

Echocardiographic Evaluation of Atrial Communications before Transcatheter Closure

Echocardiographic Evaluation of Atrial Communications before Transcatheter Closure

Published on: February 8, 2022

Area of Science:

Cardiology
Radiology
Medical Imaging

Background:

Atrial fibrillation frequently leads to thromboembolism from the left atrium (LA) and left atrial appendage (LAA), causing stroke.
Computed tomography (CT) offers a noninvasive approach for identifying LA/LAA thrombus.
The diagnostic accuracy of CT for LA/LAA thrombus requires comprehensive evaluation.

Purpose of the Study:

To perform a meta-analysis evaluating the diagnostic accuracy of CT in detecting LA/LAA thrombus.
To compare CT's performance against transesophageal echocardiography as a reference standard.

Main Methods:

A systematic literature search was conducted across major databases (PubMed, Medline, ISI Web of Knowledge, Cochrane Library) up to June 2012.
Meta-analysis techniques were employed to pool sensitivity and specificity data.
Summary receiver operating characteristic (SROC) curves were constructed to assess overall diagnostic performance.

Main Results:

Nine studies comprising 1646 patients were included in the meta-analysis.
CT demonstrated a mean sensitivity of 81% (95% CI: 70-90%) and specificity of 90% (95% CI: 88-91%) for LA/LAA thrombus detection.
The SROC analysis yielded an area under the curve of 0.93, indicating strong diagnostic capability.

Conclusions:

Computed tomography exhibits significant diagnostic accuracy for detecting LA/LAA thrombus.
CT is a highly sensitive and specific noninvasive imaging modality.
CT represents a primary noninvasive alternative to transesophageal echocardiography for LA/LAA thrombus identification, warranting further patient-level randomized trials.