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Related Concept Videos

Skin Cancer01:30

Skin Cancer

Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...

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Combining Reflectance Confocal Microscopy with Optical Coherence Tomography for Noninvasive Diagnosis of Skin Cancers via Image Acquisition
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Combining Reflectance Confocal Microscopy with Optical Coherence Tomography for Noninvasive Diagnosis of Skin Cancers via Image Acquisition

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Basal cell carcinoma: a single-center experience.

Ozan Luay Abbas1, Huseyin Borman

  • 1Department of Plastic, Reconstructive and Aesthetic Surgery, Baskent University Faculty of Medicine, 40000 Ankara, Turkey.

ISRN Dermatology
|January 16, 2013
PubMed
Summary

Basal cell carcinoma (BCC) is a common skin cancer, often linked to sun exposure. Early detection and surgical treatment are crucial for managing this condition and minimizing recurrence.

Area of Science:

  • Dermatology
  • Oncology
  • Surgical Pathology

Background:

  • Basal cell carcinoma (BCC) represents the most common type of skin cancer.
  • Its incidence is increasing, particularly among fair-skinned populations, with sun exposure as a key risk factor.
  • Early diagnosis and effective management are vital for excellent patient prognosis.

Purpose of the Study:

  • To retrospectively analyze the clinical and pathological features of surgically excised basal cell carcinomas.
  • To evaluate treatment outcomes, including reexcision rates and recurrence patterns.
  • To underscore the importance of surgical ablation in BCC management.

Main Methods:

  • Retrospective analysis of 518 basal cell carcinoma excisions from January 1994 to May 2012.

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Isolation and Characterization of a Head and Neck Squamous Cell Carcinoma Subpopulation Having Stem Cell Characteristics

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  • Data collection included patient demographics, tumor location, histological subtype, and treatment outcomes.
  • Surgical ablation was the primary treatment modality.
  • Main Results:

    • 518 BCCs were excised from 486 patients over an 18-year period.
    • The majority of patients were male, with a median age of 65.6 years; most BCCs were located on the head.
    • The nodular subtype was most prevalent, with a 6% reexcision rate for involved margins and a 6.94% recurrence rate, predominantly on the nose and periauricular/periocular areas.

    Conclusions:

    • While BCC has low mortality, its morbidity and treatment costs are substantial.
    • Established oncologic principles, diagnostic methods, surgical techniques, and follow-up protocols guide current management.
    • Surgical ablation remains the definitive treatment for basal cell carcinoma.