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Related Experiment Video

Updated: May 15, 2026

A Novel Strategy Combining Array-CGH, Whole-exome Sequencing and In Utero Electroporation in Rodents to Identify Causative Genes for Brain Malformations

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Olmsted syndrome.

Renata Elise Tonoli¹, Damiê De Villa, Renata Hübner Frainer

¹Department of Dermatology, Brazilian Society of Dermatology, Santo Antônio Hospital, Santa Casa de Midericórdia de Porto Alegre, Porto Alegre, RS, Brazil.

Case Reports in Dermatological Medicine

|January 16, 2013

Summary

This summary is machine-generated.

Olmsted syndrome is a rare congenital skin disorder causing palmoplantar keratoderma and hyperkeratotic plaques. This paper details a case and its treatment, highlighting the condition

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Area of Science:

Dermatology
Medical Genetics

Background:

Olmsted syndrome is a rare congenital disorder characterized by palmoplantar keratoderma.
It presents with symmetrical keratoderma on palms and soles and hyperkeratotic plaques around body orifices.

Purpose of the Study:

To describe a clinical case of Olmsted syndrome.
To discuss the management of this rare condition.

Main Methods:

Clinical case description.
Review of treatment strategies for Olmsted syndrome.

Main Results:

The case presented with typical clinical features of Olmsted syndrome, including palmoplantar keratoderma and periorificial plaques.
Treatment involved topical therapies, with outcomes detailed.

Conclusions:

Olmsted syndrome requires careful clinical diagnosis based on characteristic features.
Topical therapies are the mainstay of treatment, though the condition is progressive and disabling.