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Published on: April 1, 2019
Meibomian gland dysfunction in longstanding prosthetic eye wearers
Sun Young Jang1, Sang Yeul Lee, Jin Sook Yoon
1Department of Ophthalmology, Soonchunhyang Bucheon Hospital, Soonchunhyang University College of Medicine, Bucheon Korea.
The British Journal of Ophthalmology
|January 17, 2013
Summary
Meibomian gland dysfunction (MGD) significantly affects eyelids with ocular prostheses, causing discomfort. Addressing MGD in prosthetic eye patients may improve ocular comfort and eye health.
Area of Science:
- Ophthalmology
- Ocular Surface Disease
- Prosthetic Eye Care
Background:
- Ocular discomfort is common in patients with ocular prostheses.
- The role of meibomian gland dysfunction (MGD) in prosthetic eye-related discomfort is not fully understood.
Purpose of the Study:
- To investigate if meibomian gland dysfunction (MGD) contributes to ocular discomfort in patients wearing an ocular prosthesis.
- To compare the ocular surface and meibomian gland health between prosthetic eyes and healthy control eyes.
Main Methods:
- Thirty patients with unilateral ocular prostheses completed MGD symptom questionnaires.
- Eyelids underwent slit lamp examination, meibography, and Fourier-domain optical coherence tomography (FD OCT).
- Intra-individual comparisons were made between prosthetic and normal eyes.
Main Results:
- Prosthetic eyelids showed significantly higher MGD symptoms, lid abnormalities, and poorer meibomian gland function compared to normal eyelids (p<0.01).
- Tear parameters, assessed by FD OCT, were significantly lower in prosthetic eyes (p<0.01).
- Ocular symptoms strongly correlated with MGD severity and inversely with tear parameters.
Conclusions:
- Ocular prostheses are associated with significant signs of meibomian gland dysfunction (MGD).
- Clinical evaluation and management of MGD are recommended for patients with prosthetic eyes experiencing ocular discomfort.
- Targeting MGD may alleviate discomfort and improve the ocular health of prosthetic eye users.
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