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[Management of fungal pyelonephritis with percutaneous pyelostomy in infants]

Jing Shen1, Shan Xu, Li-ping Shi

  • 1Department of Urology, Children's Hospital Affiliated to Zhejiang University School of Medicine, Hangzhou 310003, China.

Zhonghua Er Ke Za Zhi = Chinese Journal of Pediatrics
|January 18, 2013
PubMed
Abstract

Insights

Fungal pyelonephritis is common in preterm infants, with Candida albicans as the primary cause. Percutaneous nephrostomy and antifungal treatment offer effective management for this serious infant kidney infection.

Area of Science:

  • Pediatric Nephrology
  • Mycology
  • Neonatology

Background:

  • Fungal pyelonephritis is a rare but serious kidney infection.
  • Preterm and low birth weight infants are particularly vulnerable.

Purpose of the Study:

  • To investigate the clinical characteristics and management strategies for fungal pyelonephritis in infants.
  • To evaluate treatment outcomes and long-term prognosis.

Main Methods:

  • Retrospective analysis of 5 infant cases with fungal pyelonephritis.
  • Inclusion of clinical data, laboratory findings, imaging features, and treatment regimens.
  • Follow-up assessment of growth, development, and renal function.

Main Results:

  • All 5 cases involved preterm, low birth weight infants.
  • Unilateral or bilateral involvement with acute renal failure observed.
  • Imaging revealed fungus balls; urine cultures confirmed Candida albicans.
  • Percutaneous nephrostomy, irrigation, and antifungal agents led to good prognosis in most cases.
  • Survivors showed normal growth and development without urinary system malformations.

Conclusions:

  • Fungal pyelonephritis frequently affects preterm infants, with Candida albicans being the predominant pathogen.
  • Percutaneous nephrostomy and drainage are crucial for relieving urinary obstruction and controlling infection.
  • Early diagnosis and prompt treatment are vital for favorable outcomes in affected infants.

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