Hemodynamic analysis of vascular stenting treatment outcome: computational fluid dynamics method vs optical flow...

Area of Science:

• Medical Imaging
• Biomedical Engineering
• Fluid Dynamics

Background:

• Digital subtraction angiography (DSA) provides hemodynamic information.
• Quantitative comparison between computational fluid dynamics method (CFDM) and optical flow method (OFM) is lacking.
• Stenting treatment is a common intervention for carotid stenosis.

Purpose of the Study:

• To apply CFDM and OFM for quantitative analysis of stenting treatment outcomes.
• To compare the effectiveness of CFDM and OFM in evaluating hemodynamic changes after stenting.
• To assess the practicality of these methods for patient treatment evaluation.

Main Methods:

• Hemodynamic analysis using CFDM and OFM on DSA data before and after stenting.
• Case study of a patient with left carotid stenosis undergoing percutaneous transluminal angioplasty and stenting.
• Utilizing Newtonian and non-Newtonian fluid models within CFDM.

Main Results:

• Improvement in blood flow velocities in the left internal carotid artery post-stenting was quantified.
• CFDM showed higher flow velocity improvements (1.91–2.13 Newtonian, 1.62–2.09 non-Newtonian) compared to OFM (0.69).
• CFDM analysis facilitated flow mapping by OFM using time-resolved DSA for estimating hemodynamic significance.

Conclusions:

• CFDM and OFM provide practical, quantitative blood flow estimations for evaluating carotid stenosis stenting outcomes.
• Both methods offer valuable quantitative data for assessing stenting treatment efficacy.
• Employing both CFDM and OFM concurrently is advantageous for comprehensive treatment evaluation.