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Bilateral appendicular bone tumors in four dogs.

Laura E Selmic¹, Stewart D Ryan, Nicole P Ehrhart

¹Department of Clinical Sciences, Animal Cancer Center, Colorado State University, Fort Collins, CO, USA. laura.selmic@colostate.edu

Journal of the American Animal Hospital Association

|January 18, 2013

Summary

Bilateral synchronous appendicular bone tumors are rare in dogs. Treatments, including radiation and surgery, offered survival times comparable to single bone tumors.

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Area of Science:

Veterinary Oncology
Comparative Pathology

Background:

Bilateral synchronous appendicular bone tumors are exceptionally rare.
This study details four canine cases with this condition.

Observation:

Dogs presented with unilateral lameness; one showed contralateral limb pain.
Technetium-99m ((99m)Tc) scintigraphy revealed bilateral lesions in distal radii, proximal humeri, or distal tibiae.
Thoracic radiographs excluded pulmonary metastases.

Findings:

Palliative radiation therapy (with or without bisphosphonates) yielded survival times of 50, 193, and 523 days.
Stereotactic radiation therapy combined with limb salvage and chemotherapy resulted in a 926-day survival.
Treatment outcomes were similar to those for solitary appendicular bone tumors.

Implications:

This study expands understanding of rare bilateral bone tumors in dogs.
Treatment strategies for single bone tumors may be applicable to bilateral presentations.
Further research into the etiology and optimal management of these rare tumors is warranted.