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Updated: May 15, 2026

A Novel Tenorrhaphy Suture Technique with Tissue Engineered Collagen Graft to Repair Large Tendon Defects
Published on: December 10, 2021
Zone 2 flexor tendon injuries: Venturing into the no man's land
Prakash P Kotwal1, Mohammed Tahir Ansari
1Department of Orthopaedics, AIIMS, Ansari Nagar, New Delhi, India.
Management of flexor tendon injuries, especially in zone 2, is evolving with advanced suture techniques and active mobilization. Future research focuses on biomolecular modulation and tissue engineering for improved tendon repair outcomes.
Area of Science:
- Orthopedics
- Hand Surgery
- Regenerative Medicine
Background:
- Flexor tendon injuries are common but management remains debated.
- Advances in suture techniques and biomechanics have improved outcomes.
- Zone 2 flexor tendon injuries present unique challenges for surgeons.
Purpose of the Study:
- To review current concepts in managing zone 2 flexor tendon injuries.
- To highlight advancements in surgical techniques and rehabilitation.
- To discuss emerging research in tendon repair.
Main Methods:
- Review of current literature on flexor tendon injury management.
- Analysis of trends in surgical repair and postoperative protocols.
- Discussion of novel approaches like biomolecular modulation and tissue engineering.
Main Results:
- Improved outcomes due to multistrand core suture techniques and active mobilization.
- Zone 2 injuries remain complex despite improved results.
- Biomolecular modulation and tissue engineering show promise for future research.
Conclusions:
- Current management strategies for zone 2 flexor tendon injuries have led to better outcomes.
- Active mobilization protocols are increasingly adopted.
- Future research directions include biomolecular and tissue engineering approaches for tendon regeneration.
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