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Updated: May 15, 2026

Drug-Induced Sleep Endoscopy (DISE) with Target Controlled Infusion (TCI) and Bispectral Analysis in Obstructive Sleep Apnea
Published on: December 6, 2016
Acute aortic dissection associated with sleep apnea syndrome
Hiromasa Yanagi1, Kiyotaka Imoto, Shin-ichi Suzuki
1Department of Cardiovascular Surgery, Fujisawa City Hospital, Fujisawa, Kanagawa, Japan.
Sleep apnea syndrome (SAS) is prevalent in acute aortic dissection patients, particularly younger, hypertensive males. This suggests SAS may be a significant risk factor for aortic dissection in this demographic.
Area of Science:
- Cardiology
- Sleep Medicine
- Vascular Surgery
Background:
- Sleep apnea syndrome (SAS) is an independent risk factor for hypertension.
- Hypertension is a major risk factor for acute aortic dissection.
- Understanding the link between SAS and acute aortic dissection is crucial for risk stratification and prevention.
Purpose of the Study:
- To determine the prevalence of SAS in patients diagnosed with acute aortic dissection.
- To identify the specific characteristics of patients who have acute aortic dissection and also have SAS.
Main Methods:
- A cohort of 95 consecutive patients with acute aortic dissection was studied.
- Sleep status and nocturnal hypoxemia were assessed in 13 patients using a portable sleep monitoring system.
Main Results:
- 12.6% of acute aortic dissection patients (12 out of 95) were diagnosed with SAS.
- SAS-positive patients were significantly younger (47.2 vs. 64.9 years), predominantly male, and had higher BMI and hypertension compared to SAS-negative patients.
- All SAS-positive patients had a history of hypertension.
Conclusions:
- Patients with acute aortic dissection and SAS are typically younger, taller, heavier males with hypertension.
- SAS may represent a significant risk factor for acute aortic dissection, especially in middle-aged men.
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