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Measuring Peptide Translocation into Large Unilamellar Vesicles
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Measuring Peptide Translocation into Large Unilamellar Vesicles

Published on: January 27, 2012

Assaying peptide translocation by the peptide transporter TAP

Marlieke L M Jongsma1, Jacques Neefjes2

  • 1Department of Cell Biology II, The Netherlands Cancer Institute, Amsterdam, The Netherlands.

Methods in Molecular Biology (Clifton, N.J.)
|January 19, 2013
PubMed
Summary

The Transporter Associated with Antigen Processing (TAP) moves peptides into the endoplasmic reticulum for MHC class I presentation. This study outlines methods to assay TAP activity and identify its inhibitors.

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