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Malignant gastric lymphoma with spontaneous perforation
Satoko Shimada1, Tokichi Gen, Hiroyuki Okamoto
1Department of General Surgery, JA Toride Medical Centre, Toride-shi, Japan. stomiya@juntendo.ac.jp
BMJ Case Reports
|January 19, 2013
Summary
Spontaneous perforation of malignant gastric lymphoma is rare, occurring in less than 5% of cases. This study documents a rare instance of spontaneous gastric perforation in a patient with malignant lymphoma, highlighting its infrequent occurrence outside of chemotherapy.
Area of Science:
- Gastroenterology
- Oncology
- Surgical Pathology
Background:
- Malignant gastric lymphoma is a rare malignancy, typically diffuse large B-cell lymphoma, comprising 1% of primary gastric cancers.
- Gastric perforations are often associated with malignancy, primarily gastric carcinoma, as reported by Toyota et al.
- Perforations in malignant gastric lymphoma are uncommon, with less than 5% of cases reported by Fukuda et al.
Observation:
- Perforations during chemotherapy for gastric malignancies are known but rare in non-chemotherapy patients.
- Spontaneous perforation of malignant gastric lymphoma is exceptionally rare.
- This case represents the 27th reported instance in the Japanese literature over the past 25 years.
Findings:
- The study highlights the rarity of spontaneous gastric perforation in the context of malignant lymphoma.
- It underscores the low incidence of perforation in malignant gastric lymphoma, especially in the absence of chemotherapy.
- The findings contribute to the limited existing literature on spontaneous gastric lymphoma perforation.
Implications:
- Increased awareness of spontaneous perforation as a potential complication of malignant gastric lymphoma.
- Further research may be warranted to understand the mechanisms and risk factors for spontaneous perforation.
- This case adds valuable data to the scarce reports, aiding future clinical management and diagnosis.
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