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Updated: May 15, 2026

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Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery
Published on: July 5, 2021
Endoscopic surgery in the skull base unit: experience in the first 72 cases
Juan R Gras-Cabrerizo1, Fernando Muñoz-Hernández, Joan R Montserrat-Gili
1Servicio de Otorrinolaringología, Hospital de la Santa Creu i Sant Pau, Universidad Autónoma de Barcelona, Barcelona, España. jgras@santpau.cat
Acta Otorrinolaringologica Espanola
|January 22, 2013
Summary
Endoscopic endonasal skull base surgery is effective for various lesions, including pituitary adenomas and CSF leaks. Multidisciplinary collaboration is key to successful outcomes in these complex procedures.
Area of Science:
- Neurosurgery
- Otolaryngology
- Endoscopic Skull Base Surgery
Background:
- Endoscopic endonasal skull base surgery requires a multidisciplinary team for optimal development and expanded indications.
- This study presents the experience of a center in treating skull base lesions using an endonasal endoscopic approach.
Purpose of the Study:
- To present the center's experience with endonasal endoscopic surgery for skull base lesions.
- To evaluate the efficacy and outcomes of this approach in a diverse patient group.
Main Methods:
- Retrospective analysis of 72 patients treated between January 2008 and January 2012.
- Utilized various endonasal endoscopic approaches including transsphenoidal, transmaxillary, and expanded endonasal techniques.
- Procedures included Draf IIb/III and ethmoidal/sphenoidal approaches.
Main Results:
- Common pathologies included pituitary adenomas (36), cerebrospinal fluid (CSF) leaks (10), and inverted papillomas (5).
- Total resection rates for pituitary adenomas were 61%, with 86% successful repair for CSF leaks.
- Complications occurred in 29% of patients, with 6 major complications.
Conclusions:
- Multidisciplinary collaboration is crucial for success in endoscopic endonasal skull base surgery.
- The study highlights the center's experience and the effectiveness of the endonasal endoscopic approach for skull base pathologies.
