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Auricular chondritis and thrombotic microangiopathy: an unusual combination revealing systemic lupus erythematosus
Nathalia Bellon1, Nadia Anguel, Christophe Vandendries
1AP-HP, Department of Internal Medicine, Bicêtre University Medical Center, 78, rue du Général-Leclerc, 94275 Le-Kremlin-Bicêtre, France.
Thrombotic microangiopathy is a severe disorder, which is a cause of stroke in young patients. Etiologic investigations are mandatory to diagnose underlying disease. Systemic lupus erythematosus is one of the diseases, which can be associated with thrombotic microangiopathy. Although lupus diagnosis is usually easy, relying on characteristic clinical manifestations, rare symptoms can be misinterpreted. We report here a case of polychondritis, which was the first manifestation of a lupus-associated thrombotic microangiopathy.
Thrombotic microangiopathy is a severe disorder, which is a cause of stroke in young patients. Etiologic investigations are mandatory to diagnose underlying disease. Systemic lupus erythematosus is one of the diseases, which can be associated with thrombotic microangiopathy. Although lupus diagnosis is usually easy, relying on characteristic clinical manifestations, rare symptoms can be misinterpreted. We report here a case of polychondritis, which was the first manifestation of a lupus-associated thrombotic microangiopathy.
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The first classification is based on the development of the disease, and it includes the following categories: