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[Kinetics of the transformation of dihydroambazone into ambazone]
N Miosga1, W Roemer, R Amlacher
1Akademie der Wissenschaften der DDR.
Die Pharmazie
|January 1, 1990
Abstract:
The oxidation of dihydroambazone (1) by oxygen is dependent on the pH-values of the solutions used. This transformation can be inhibited and excluded, respectively, by ascorbic acid using defined concentrations. The oxidation product ambazone (2) was determined spectroscopically at different pH-values. The rate of transformation in serum depends on the temperature and can also be inhibited with ascorbic acid.