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A High Content Imaging Assay for Identification of Botulinum Neurotoxin Inhibitors
Published on: November 14, 2014
A novel method for the preparation of a neurotoxic complex
Bum Han Ryu1, Eunjin Jang, Hansol Ju
1Department of Molecular Science and Technology, Graduate School of Interdisciplinary Programs, Ajou University, Suwon, South Korea.
Analytical Biochemistry
|January 22, 2013
Abstract:
Neurodegenerative diseases such as Alzheimer's disease (AD) and Parkinson's disease (PD) can be attributed to the specific degeneration of neuronal cells in the brain. However, the natures and action modes of toxic species remain largely unknown. Here, we present a simple and fast method for the preparation of neurotoxic complex with α-synuclein, which is implicated in PD.
