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Related Concept Videos

Circadian Rhythms and Gene Regulation02:19

Circadian Rhythms and Gene Regulation

The biological clock is involved in many aspects of regulating complex physiology in all animals. It was in 1935 when German zoologists, Hans Kalmus and Erwin Bünning, discovered the existence of circadian rhythm in Drosophila melanogaster. However, the internal molecular mechanisms behind the circadian clock remained a mystery until 1984, when Jeffrey C. Hall, Michael Rosbash, and Michael W. Young discovered the expression of the Per gene oscillating over a 24-hour cycle. In subsequent years,...
Circadian Rhythms and Gene Regulation02:19

Circadian Rhythms and Gene Regulation

The biological clock is involved in many aspects of regulating complex physiology in all animals. It was in 1935 when German zoologists, Hans Kalmus and Erwin Bünning, discovered the existence of circadian rhythm in Drosophila melanogaster. However, the internal molecular mechanisms behind the circadian clock remained a mystery until 1984, when Jeffrey C. Hall, Michael Rosbash, and Michael W. Young discovered the expression of the Per gene oscillating over a 24-hour cycle. In subsequent years,...
Biological Clocks and Seasonal Responses02:45

Biological Clocks and Seasonal Responses

The circadian—or biological—clock is an intrinsic, timekeeping, molecular mechanism that allows plants to coordinate physiological activities over 24-hour cycles called circadian rhythms. Photoperiodism is a collective term for the biological responses of plants to variations in the relative lengths of dark and light periods. The period of light-exposure is called the photoperiod.
Regulation of Food Intake01:30

Regulation of Food Intake

Short-term regulation of food intake primarily involves neural signals from the gastrointestinal (GI) tract, blood nutrient levels, and GI tract hormones. Communication between the gut and brain via vagal nerve fibers plays a significant role in evaluating the contents of the gut. Clinical studies have shown that protein ingestion produces a more prolonged response in these nerve fibers compared to an equivalent amount of glucose. Additionally, the activation of stretch receptors caused by GI...
Diencephalon: Hypothalamus and Coordination01:23

Diencephalon: Hypothalamus and Coordination

The hypothalamus is a small yet highly complex and essential brain region that plays a crucial role in regulating various bodily functions. Anatomically, it is located at the base of the brain, just above the brainstem and below the thalamus, forming part of the limbic system.
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Hunger and thirst are fundamental physiological drives crucial for maintaining homeostasis and ensuring the survival of both humans and animals. These drives are regulated through complex interactions between the brain, hormones, and sensory receptors.
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Manipulation of Rhythmic Food Intake in Mice Using a Custom-Made Feeding System
07:34

Manipulation of Rhythmic Food Intake in Mice Using a Custom-Made Feeding System

Published on: December 16, 2022

Hypothalamic clocks and rhythms in feeding behaviour.

David A Bechtold1, Andrew S I Loudon

  • 1University of Manchester, Manchester, UK. david.bechtold@manchester.ac.uk

Trends in Neurosciences
|January 22, 2013
PubMed
Summary
This summary is machine-generated.

Daily rhythms influence our health, with the body

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Last Updated: May 15, 2026

Manipulation of Rhythmic Food Intake in Mice Using a Custom-Made Feeding System
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Published on: December 16, 2022

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Area of Science:

  • Chronobiology and Metabolic Health
  • Molecular and Behavioral Rhythms

Background:

  • Physiological processes exhibit daily rhythms, from sleep to molecular epigenetic coding.
  • Circadian clock networks, composed of core clock and clock-controlled genes, regulate these rhythms.
  • A strong link exists between circadian clocks and metabolic regulation.

Purpose of the Study:

  • To explore the influence of the circadian clock on feeding behavior and metabolism.
  • To understand how disruptions in daily rhythms contribute to obesity and diabetes.
  • To highlight the importance of circadian timing in a 24-hour society.

Main Methods:

  • Review of existing research on circadian rhythms and metabolism.
  • Analysis of the role of feeding behavior as a circadian entrainment stimulus.
  • Investigation into the link between circadian disruption and metabolic diseases.

Main Results:

  • Feeding behavior shows a strong circadian rhythm.
  • Food intake is a potent stimulus for entraining the body's clocks.
  • Disturbances in daily rhythms are implicated in obesity and diabetes development.

Conclusions:

  • The circadian clock significantly influences eating patterns and metabolic health.
  • Understanding circadian influences on food intake is crucial for public health.
  • Further research is needed to address the impact of modern lifestyles on circadian rhythms and metabolic disease.