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A quantitative structure-activity relationship study for local anesthetic activity of mono-and
Research Communications in Chemical Pathology and Pharmacology
|February 1, 1990
Abstract:
The local anesthetic activity of a series of arylquinuclidinylcarbinols is shown to be significantly correlated with their lipophilic character, suggesting that lipophilicity is an important factor for the local anesthetic action of drugs.
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