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A Bioluminescent and Fluorescent Orthotopic Syngeneic Murine Model of Androgen-dependent and Castration-resistant Prostate Cancer
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A Bioluminescent and Fluorescent Orthotopic Syngeneic Murine Model of Androgen-dependent and Castration-resistant Prostate Cancer

Published on: March 6, 2018

A novel canine model for prostate cancer

Jill M Keller1, George R Schade, Kimberly Ives

  • 1Department of Urology, University of Michigan, Ann Arbor, Michigan 48109-5940, USA.

The Prostate
|January 22, 2013
PubMed
Summary

Researchers developed a new canine prostate cancer model. This minimally invasive dog model closely mimics human prostate cancer, aiding research into cancer progression and metastasis.

Failed At:

2026-06-19T13:32:44.115215+00:00

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Mice have long served as models for studying human biology and pathology because of their phylogenetic and physiological similarity with humans. They are also easy to maintain and breed in the laboratory, and hence, many inbred strains are now available for research. Studies on mice have contributed immeasurably to our understanding of cancer biology.
The development of transgenic, knockout, and knock-in mice has led to an exponential increase in their use as model organisms in research,...

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