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Updated: May 15, 2026
08:05
Occlusion of the Great and Small Saphenous Vein Using Copolymeric Glue Based on N-Butyl Cyanoacrylate and Methacryloxy Sulfolane
Published on: December 9, 2022
Body mass index and primary chronic venous disease--a cross-sectional study
H D Vlajinac1, J M Marinkovic, M Z Maksimovic
1Institute of Epidemiology, Faculty of Medicine, University of Belgrade, Belgrade, Serbia. kristiv@eunet.rs
Summary
Overweight and obesity are linked to more advanced stages of chronic venous disease (CVD). This association between higher body mass index and clinical categories of CVD is independent of other risk factors.
Area of Science:
- Vascular Medicine
- Epidemiology
- Public Health
Background:
- Chronic venous disease (CVD) is a common condition affecting leg veins.
- The clinical, etiologic, anatomic, and pathophysiologic (CEAP) classification system categorizes CVD severity.
- The relationship between body weight and CVD progression requires further investigation.
Purpose of the Study:
- To determine if overweight and obesity correlate with the clinical (C) category of CEAP classification in patients with CVD.
- To analyze the association between body mass index (BMI) and the severity of chronic venous disease.
Main Methods:
- A cross-sectional study involving 1116 adult patients with primary CVD in Serbia.
- Data collection included demographic, anthropometric (including BMI), and clinical data.
- Univariate and multivariate logistic regression analyses were employed to assess associations.
Main Results:
- Overweight (42.7%) and obese (15.8%) patients showed significantly more advanced CEAP C categories compared to normal-weight individuals.
- The association between higher BMI and advanced CVD was more pronounced in obese patients.
- No significant difference in venous reflux was observed between groups, though venous obstruction was related to overweight/obesity in univariate analysis.
Conclusions:
- Overweight and obesity are significantly associated with more advanced clinical categories of chronic venous disease.
- This relationship is independent of age, sex, and other potential risk factors.
- Findings highlight the importance of weight management in mitigating CVD progression.
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