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Relaxometric determination of binding between Mn(II)-UDP and Mn(II)-UDP-glucose in aqueous solution
Etelka Farkas1, Orsolya Szabó, Gyula Tircsó
1Department of Inorganic and Analytical Chemistry, University of Debrecen, H-4010 Debrecen, P.O. Box 21, Hungary. efarkas@science.unideb.hu
Carbohydrate Research
|January 23, 2013
Abstract:
The applicability of relaxometry for the determination of formation constants of Mn(II)-UDP (logK=3.78) and Mn(II)-UDP-glucose (logK=2.98) complexes is demonstrated. The obtained value indicates a well-defined interaction between Mn(II) and UDP-glucose in aqueous solution (pH=5.50) with ΔG = -4.07 kcal/mol.

