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Separation of Sister Chromatids

Separation of Sister Chromatids

At the transition from prophase to metaphase, there is a reduction in cohesion along the chromosomal arms, resulting in the resolution of sister chromatids. However, residual cohesin connections remain to hold the sister chromatids together until the transition from metaphase to anaphase. The residual connection prevents any premature separation of sister chromatids, blocking the risks of aneuploidy within the daughter cells.
At the onset of anaphase, separase, a proteolytic enzyme, is...

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Related Experiment Video

Updated: May 14, 2026

Murine Prostate Micro-dissection and Surgical Castration

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Published on: May 11, 2016

Editorial: separation surgery

Charles Fisher, Juliet Batke

Journal of Neurosurgery. Spine

|January 24, 2013

Summary

No abstract available in PubMed .

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