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Published on: January 17, 2025
Resected pleomorphic carcinoma of the gallbladder
Masanari Shimada1, Shinichi Kadoya, Yasuko Tanada
1Department of Surgery, Saiseikai Takaoka Hospital, Takaoka City, Japan.
Case Reports in Gastroenterology
|January 24, 2013
Summary
This study presents a rare case of stage I pleomorphic carcinoma of the gallbladder in a 77-year-old woman. Curative surgery was successful, with no recurrence observed for 1.5 years, highlighting the need for more case reports.
Area of Science:
- Gastroenterology
- Surgical Oncology
- Pathology
Background:
- Pleomorphic carcinoma of the gallbladder is an exceedingly rare malignancy.
- Few case reports exist in the medical literature, limiting understanding of its behavior.
Observation:
- A 77-year-old female patient presented with nausea and anorexia.
- Imaging revealed irregular thickening of the gallbladder wall.
- Surgical exploration identified adherence to the transverse colon without distant metastasis.
Findings:
- Histopathology confirmed a rare primary pleomorphic gallbladder carcinoma.
- The tumor demonstrated a coexistence of adenocarcinoma, squamous cell carcinoma, and sarcomatous components.
- The patient was diagnosed with stage I disease and underwent curative cholecystectomy with partial colectomy.
Implications:
- This case demonstrates the possibility of curative surgical resection for stage I pleomorphic gallbladder carcinoma.
- Further case accumulation is crucial for defining diagnostic criteria and understanding the biological behavior of this rare tumor.
