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Updated: May 14, 2026
Direct Mouse Trauma/Burn Model of Heterotopic Ossification
Published on: August 6, 2015
[A report of 4 cases about gluteal heterotopic ossification caused by injection]
Jun-Ling Xu1, Shu-Lan Shang, Guo-Sheng Yu
1The 8th Department of Orthopaedics, Cangzhou Hospital of TCM and Western Medicine, Cangzhou 061000, Hebei, China. junlingx@126.com
Objective:
To study the pathogenesis and treatment of gluteal heterotopic ossification caused by injection.
Methods:
From April 2006 to May 2011, 4 old female patients with gluteal heterotopic ossification caused by injection were treated by resection. The average age was 71 years old ranging from 67 to 76. The illness were bilateral,the clinical character was pain and hard nodules in the both hip. The X-ray, CT and pathology matched the diagnosis of heterotopic ossification. Two of them were treated by totally removing the ossified tissues, and loosing the spastic and adhesive soft tissues. The other two were treated with local resection and soft-tissue lysis.
Results:
The wound of all patients healed well, and there were no complication. All patients were followed-up from 2 to 64 months(averaged 26 months). There were no lump and pain in the location of surgical resection.
Conclusion:
Gluteal heterotopic ossification caused by injection is the drug reaction produced by injecting benzyl alcohol or other drugs,and happens in adults. The key for the treatment is to remove part or all of the painful lump,and loose the local fascia and other soft tissues of the gluteal muscles.
