Related Experiment Video
Updated: Sep 12, 2026

Establishment of a Modified Ferric Chloride-Induced Superior Sagittal Sinus Thrombosis
Published on: December 30, 2025
Cavernous Sinus Thrombosis Following the Use of Oral Contraceptive Pills in a Young Woman: A Case Report
Zohreh Akbari1, Ali Salami2, Ali Movahedi1
1Department of Anesthesia Neyshabur University of Medical Sciences Neyshabur Iran.
Abstract:
Cavernous sinus thrombosis (CST) is a rare and potentially life-threatening subtype of cerebral venous sinus thrombosis that often poses diagnostic challenges in emergency settings. We report a 34-year-old woman with a one-year history of oral contraceptive pill (OCP) use for polycystic ovary syndrome who presented with severe headache, seizures, decreased level of consciousness, and bilateral eyelid edema. Non-contrast brain computed tomography showed extensive intracerebral hemorrhage with findings suggestive of CST. Because of clinical instability, advanced venous imaging (CTV/MRV) could not be performed, and the diagnosis remained presumptive. The patient was treated with intravenous unfractionated heparin, intracranial pressure control and subsequent decompressive craniectomy because of progressive neurological deterioration. This case highlights the need for a high index of suspicion, prompt imaging, and early anticoagulation in patients with suspected CST and prothrombotic risk factors such as OCP use.
Related Concept Videos
Venous Thrombosis I: Introduction
Anticoagulant Drugs: Vitamin K Antagonists and Direct Oral Anticoagulants
Warfarin, a prominent vitamin K antagonist family member, exerts its effect by inhibiting the enzyme VKORC1 (vitamin K epoxide reductase complex 1). By hindering this enzyme, warfarin...
Venous Thrombosis III: Interprofessional Care
Venous Thrombosis II: Clinical Manifestations and Diagnostic Studies
Esophageal Varices-II: Clinical Features and Management
In the initial assessment, a thorough review of the patient's medical history is vital to identify risk factors such as liver disease, alcohol abuse, or...