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Related Concept Videos

Targeted Cancer Therapies02:57

Targeted Cancer Therapies

The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against specific...
Cancer Therapies02:49

Cancer Therapies

Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
Combination Therapies and Personalized Medicine02:50

Combination Therapies and Personalized Medicine

Combining two or more treatment methods increases the life span of cancer patients while reducing damage to vital organs or tissue from the overuse of a single treatment. Combination therapy also targets different cancer-inducing pathways, thus reducing the chances of developing resistance to treatment.
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...

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Updated: May 14, 2026

A Comprehensive Procedure to Evaluate the In Vivo Performance of Cancer Nanomedicines
07:59

A Comprehensive Procedure to Evaluate the In Vivo Performance of Cancer Nanomedicines

Published on: March 4, 2017

Nanomedicine in chemoradiation.

Seth M Miller1, Andrew Z Wang

  • 1Department of Radiation Oncology & Laboratory of Nano- & Translational Medicine, University of North Carolina, Chapel Hil, NC, USA.

Therapeutic Delivery
|January 25, 2013
PubMed
Summary

Nanomedicine offers a novel approach to enhance chemoradiotherapy, a standard cancer treatment. This review explores how nanoparticles can improve drug delivery and therapeutic outcomes in cancer care.

Area of Science:

  • Oncology
  • Nanomedicine
  • Radiotherapy

Background:

  • Chemoradiotherapy, combining chemotherapy and radiotherapy, is a cornerstone in treating various cancers.
  • Improving the therapeutic index of chemoradiation is a key objective in cancer research.
  • Nanomedicine presents promising opportunities to advance chemoradiotherapy efficacy.

Purpose of the Study:

  • To review the integration of nanomedicine into chemoradiotherapy protocols.
  • To evaluate the potential impact of nanotechnology on chemoradiation treatment outcomes.

Main Methods:

  • Literature review of nanomedicine applications in chemoradiotherapy.
  • Analysis of nanoparticle properties relevant to drug delivery in cancer treatment.

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Sample Extraction and Simultaneous Chromatographic Quantitation of Doxorubicin and Mitomycin C Following Drug Combination Delivery in Nanoparticles to Tumor-bearing Mice
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Sample Extraction and Simultaneous Chromatographic Quantitation of Doxorubicin and Mitomycin C Following Drug Combination Delivery in Nanoparticles to Tumor-bearing Mice

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Last Updated: May 14, 2026

A Comprehensive Procedure to Evaluate the In Vivo Performance of Cancer Nanomedicines
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Published on: March 4, 2017

Modeling Brain Metastasis by Internal Carotid Artery Injection of Cancer Cells
10:01

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Sample Extraction and Simultaneous Chromatographic Quantitation of Doxorubicin and Mitomycin C Following Drug Combination Delivery in Nanoparticles to Tumor-bearing Mice
08:57

Sample Extraction and Simultaneous Chromatographic Quantitation of Doxorubicin and Mitomycin C Following Drug Combination Delivery in Nanoparticles to Tumor-bearing Mice

Published on: October 5, 2017

Main Results:

  • Nanoparticles offer unique advantages for targeted drug delivery in chemoradiation.
  • Potential for improved efficacy and reduced toxicity of chemoradiotherapy.

Conclusions:

  • Nanomedicine holds significant promise for enhancing chemoradiotherapy.
  • Further research into nanoparticle-based drug delivery systems is warranted to optimize cancer treatment.