Related Experiment Videos
Acanthamoeba keratitis in non-contact lens wearers
S Sharma1, M Srinivasan, C George
1Department of Ocular Microbiology, Aravind Eye Hospital, Madurai, India.
Archives of Ophthalmology (Chicago, Ill. : 1960)
|May 1, 1990
Summary
Acanthamoeba keratitis, an eye infection, can be diagnosed using simple lab methods. Topical Neosporin drops effectively treated corneal infiltrates in non-contact lens wearers.
Area of Science:
- Ophthalmology
- Infectious Diseases
- Microbiology
Background:
- Acanthamoeba keratitis (AK) is a serious eye infection, often linked to contact lens wear.
- This study focuses on non-contact lens wearers diagnosed with AK.
Purpose of the Study:
- To report on the diagnosis and treatment outcomes of Acanthamoeba keratitis in patients not using contact lenses.
- To evaluate the efficacy of topical antibiotics and antifungals in treating this condition.
Main Methods:
- Diagnosis of nine Acanthamoeba keratitis cases using simple laboratory techniques.
- Treatment regimens included topical neomycin-polymyxin B-bacitracin (Neosporin) alone or with miconazole nitrate or ketoconazole.
- Follow-up data was collected for a subset of patients.
Main Results:
- Simple laboratory methods proved adequate for diagnosing Acanthamoeba keratitis.
- Complete resolution of corneal infiltrates was observed in four patients treated with topical medications.
- Two patients achieved resolution with Neosporin alone, and two with Neosporin plus miconazole.
Conclusions:
- Acanthamoeba keratitis can occur in individuals not wearing contact lenses.
- Topical Neosporin drops demonstrate efficacy in resolving corneal infiltrates caused by Acanthamoeba species.
- Prompt diagnosis and appropriate topical therapy are crucial for managing Acanthamoeba keratitis.